Vitamin B Complex

Vitamin B Complex is a group of water-soluble vitamins that play essential roles in various bodily functions, including energy metabolism, nerve function, and red blood cell formation [1]. This complex includes B vitamins such as B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin) [2]. 

While traditionally recognized for their involvement in metabolic processes, emerging research suggests that certain B vitamins within the complex might have implications for cancer treatment [2].

• Breast Cancer: Research indicates that folate (B9) supplementation might influence gene expression in breast cancer cells, potentially impacting tumor progression [2].
• Colorectal Cancer: B vitamins like B6 have been studied for their potential to modulate inflammation in colorectal cancer, which plays a role in disease progression [10].
• Gastric Cancer: Vitamin B complex's effect on immune responsiveness has been investigated in gastric cancer patients post-surgery [2].
• Leukemia: B vitamins' roles in DNA synthesis make them relevant in leukemia treatment, where abnormal cell division occurs [1].

Enhanced Immune Checkpoint Inhibitor Response: B vitamins could modulate immune responses, potentially enhancing the effects of immune checkpoint inhibitors.