Probiotics-15B

Probiotics are live microorganisms that confer health benefits when consumed in adequate amounts [1]. While primarily known for their role in promoting gut health and improving digestion, research suggests potential benefits of probiotics in cancer treatment [2]. Studies indicate that probiotics can modulate the gut microbiota, enhance immune response, and influence various physiological processes, which may be advantageous in inhibiting tumor progression and bolstering cancer therapy response [2].

• Breast Cancer: Probiotics have demonstrated immunomodulatory effects and potential in modulating the gut microbiota to influence breast cancer progression [12].
• Colorectal Cancer: Studies suggest that probiotics and their bioactive compounds may impact colorectal cancer development and progression by influencing the gut microbiota. [13].
• Gastrointestinal Toxicity: Probiotics show promise in preventing gastrointestinal toxicity induced by cancer therapy, potentially improving patients' quality of life [14]. 
• General Cancer Management: Probiotics have the potential to complement cancer treatment by modulating the immune system and creating an environment less favorable for cancer growth [10].

Combination therapy possibilities with probiotics:

• Increased Sensitivity to Chemotherapy: Studies suggest that probiotics may enhance the sensitivity of cancer cells to chemotherapy agents, potentially improving treatment outcomes [10].
• Synergy with Immunotherapy: Probiotics could augment the effects of immunotherapy by modulating the immune response and promoting the recognition of cancer cells by immune cells [8].
• Effect on Tumor Microenvironment: Probiotics may play a role in altering the tumor microenvironment, making it less conducive to cancer progression and potentially enhancing the effectiveness of other treatments [10].
• Targeted Drug Delivery: Research hints at probiotics' ability to serve as carriers for targeted drug delivery, delivering therapeutic agents directly to cancer cells [11].