Ashwagandha

Ashwagandha is a medicinal herb recognized in Ayurvedic formulations for its ability to combat stress, fatigue, pain, and certain diseases [1]. Recent studies have explored its potential application in cancer treatment, focusing on its ability to modulate various cellular pathways [3].

• Breast Cancer: Ashwagandha supplementation demonstrated a reduction in chemotherapy-induced fatigue and improved quality of life in breast cancer patients [6].
• Prostate Cancer: Withaferin A, a key component of Ashwagandha, exhibited anti-cancer effects by inhibiting growth and inducing apoptosis in prostate cancer cells [10].
• Colon Cancer: Ashwagandha extract showed potential in inhibiting the proliferation of colon cancer cells and inducing cell cycle arrest [10].

Lung Cancer: Ashwagandha's immune-modulating effects may contribute to improved outcomes in lung cancer treatment, though further research is needed [11].

• Increased Sensitivity to Chemotherapy: Studies suggest that Ashwagandha could sensitize cancer cells to chemotherapy agents, potentially enhancing treatment effectiveness [7].
• Synergy with Radiation Therapy: Ashwagandha's radioprotective and immune-enhancing effects may complement radiation therapy, leading to better therapeutic outcomes [8].

Targeting Cancer Stem Cells: Emerging research indicates Ashwagandha's potential to target cancer stem cells, which play a role in treatment resistance and tumor recurrence [9].